Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-Chloro-5-nitro-2(1H)-pyridinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 5-Nitropyridin-2-ol | HCID 79453 | — |
| 반응물 | Potassium Chlorate | HCID 6426889 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-Chloro-5-nitro-2(1H)-pyridinone | HCID 336289 | — |
반응 단계
5-Nitro-2-pyridone (Aldrich Chemical Company) (100 g, 0.71 mol) was added to 1 liter conc. HCl at room temperature, followed by the dropwise addition of a solution of potassium chlorate (87.5 g, 0.71 mol) in 1.2 liter water. A solid material formed during the addition. The mixture was stirred overnight, filtered, and the collected material recrystallized from 50 percent aqueous ethanol. The yield was 77.2 g, 62 percent, m.p. 196°-198° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04548888 |
| 출처 데이터셋 | uspto-grants-1985_10 |
| ORD ID | ord-14f5395969a04bf0b5ae561b9969b5b2 |
| 출처 메모 | uspto-grants-1985_10 |