Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nitromethane → Methyl 3-(4-chlorophenyl)-4-nitrobutanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nitromethane | HCID 6375 | — |
| 반응물 | 1,1,3,3-Tetramethylguanidine | HCID 66460 | — |
| 반응물 | Methyl 3-(4-chlorophenyl)-2-propenoate | HCID 98955 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | Methyl 3-(4-chlorophenyl)-4-nitrobutanoate | HCID 14931333 | — |
반응 단계
A mixture of 290 g of p-chlorocinnamic acid, methyl ester, 500 g of nitromethane and 39 g of tetramethylguanidine is allowed to stir for 72 hours. The solution is diluted with ethyl ether and aqueous hydrochloric acid solution (1 N, 1 liter) is added. The organic layer is separated, dried over anhydrous magnesium sulfate, and evaporated to give 4-nitro-3-(4-chlorophenyl)butanoic acid methyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04548947 |
| 출처 데이터셋 | uspto-grants-1985_10 |
| ORD ID | ord-e8769266aa604824bfe4c0763b4a3ee2 |
| 출처 메모 | uspto-grants-1985_10 |