참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 3-Hydroxybenzaldehyde | HCID 101 | — |
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | Formic Acid | HCID 284 | — |
| 반응물 | 3-Methylpiperidine | HCID 79081 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-[(3-Methylpiperidin-1-yl)methyl]phenol | HCID 13364666 | — |
반응 단계
24.4 g (0.2 mol) of 3-hydroxybenzaldehyde are mixed with 40 ml (about 0.4 mol) of 3-methylpiperidine and 20 ml (about 0.52 mol) of 100% formic acid with cooling and then stirred for 2 hours at 120° C. When the reaction mixture has cooled to room temperature, it is poured into water and rendered alkaline with ammonia, and the precipitated solid is filtered off and recrystallised from ethanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04727081 |
|---|
| 출처 데이터셋 | uspto-grants-1988_02 |
|---|
| ORD ID | ord-e9c53b21b5524c4296badbb52530d5b3 |
|---|
| 출처 메모 | uspto-grants-1988_02 |
|---|
