N-(4-nitrophenyl)pentanamide → N-(4-aminophenyl)pentanamide

HRID 46497

반응식

HRID 46497 반응식
[N+:1]([C:4]1[CH:16]=[CH:15][C:7]([NH:8][C:9](=[O:14])[CH2:10][CH2:11][CH2:12][CH3:13])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:8][C:9](=[O:14])[CH2:10][CH2:11][CH2:12][CH3:13])=[CH:15][CH:16]=1

참가 물질

4

반응물 1

HCID 3762929N-(4-nitrophenyl)pentanamide

생성물 1

HCID 1725711N-(4-aminophenyl)pentanamide

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A solution of 4'-nitrovaleranilide (13.33 g., 0.06 mole) in absolute ethanol (750 ml.) is hydrogenated over 10% palladium on charcoal (2 g.) until the theoretical absorption is achieved. The catalyst is removed and the solvent is removed in vacuo. The residue is recrystallized from butyl chloride to yield 9.0 g., m.p. 81°-83° C.

후처리

  1. customThe catalyst is removed
  2. customthe solvent is removed in vacuo
  3. customThe residue is recrystallized from butyl chloride
  4. customto yield 9.0 g

출처 및 근거

ORD 기록
ord-3396c84eaf1e4e19806d6ff0038281c7
출처 데이터셋
uspto-grants-1979_11
특허 번호
US04173646

연결된 노트

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