Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,2,2-Trifluoroethylhydrazine → 4,5-dihydro-2-[2-(2,2,2-trifluoroethyl)hydrazino]-1H-imidazole, hydroiodide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,2,2-Trifluoroethylhydrazine | HCID 78740 | — |
| 반응물 | 1H-Imidazole, 4,5-dihydro-2-(methylthio)-, hydriodide (1:1) | HCID 12221228 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4,5-dihydro-2-[2-(2,2,2-trifluoroethyl)hydrazino]-1H-imidazole, hydroiodide | HCID 131714398 | — |
반응 단계
To a solution of 12.2 g of 2-methylthioimidazoline, hydroiodide in 30 ml of ethanol was slowly added 12.6 g of 2,2,2-trifluoroethyl hydrazine, dropwise over 30 minutes. This mixture was refluxed overnight, then evaporated to an oil which crystallized on standing, giving 4,5-dihydro-2-[2-(2,2,2-trifluoroethyl)hydrazino]-1H-imidazole, hydroiodide, a one gram portion of which was reacted as described in Example 33, giving 1.0 g of the desired product, mp>290° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04550169 |
| 출처 데이터셋 | uspto-grants-1985_10 |
| ORD ID | ord-67b5c6a5a2cd471481aa92f5eaf23e6f |
| 출처 메모 | uspto-grants-1985_10 |