Hydrazine → 2-Hydrazino-3,3'-bipyridine

HRID 465131노트

반응식

HRID 465131 반응식
Br[C:2]1[C:7]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:6][CH:5]=[CH:4][N:3]=1.[NH2:14][NH2:15]>N1C=CC=CC=1>[NH:14]([C:2]1[C:7]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:6][CH:5]=[CH:4][N:3]=1)[NH2:15]

참가 물질

4

반응물 2

HCID 9321HydrazineHCID 135337192-Bromo-3,3'-bipyridine

생성물 1

HCID 135337152-Hydrazino-3,3'-bipyridine

시약·촉매·용매 1

HCID 1049Pyridine용매

반응 조건

온도
100 °C

실험 절차

A mixture of 16.46 g of 2'-bromo-3,3'-bipyridine, 24 ml of anhydrous hydrazine and 500 ml of dry pyridine was heated at 100° C. for 3 days. The solvent was removed under vacuum, toluene was added and removed and the residue was partitioned between saturated aqueous sodium carbonate and methylene chloride. The organic layer was dried, the solvent removed under vacuum and the residue crystallized from methylene chloride-hexane, giving 2'-hydrazino-3,3'-bipyridine as tan crystals.

후처리

  1. customThe solvent was removed under vacuum, toluene
  2. additionwas added
  3. customremoved
  4. customthe residue was partitioned between saturated aqueous sodium carbonate and methylene chloride
  5. customThe organic layer was dried
  6. customthe solvent removed under vacuum
  7. customthe residue crystallized from methylene chloride-hexane

출처 및 근거

ORD 기록
ord-be94748dd56543058014dafbf39d5368
출처 데이터셋
uspto-grants-1985_10
특허 번호
US04550166

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