Metam-sodium → Sodium 3-[2-(2-amino-4-thiazolyl)acetamido]2-oxoazetidine-1-sulfonate

HRID 465179노트

반응식

HRID 465179 반응식
ClCC([NH:5][C:6]1[S:7][CH:8]=[C:9]([CH2:11][C:12]([NH:14][CH:15]2[CH2:18][N:17]([S:19]([O-:22])(=[O:21])=[O:20])[C:16]2=[O:23])=[O:13])[N:10]=1)=O.[Na+:24].CNC(=S)[S-].[Na+]>O>[NH2:5][C:6]1[S:7][CH:8]=[C:9]([CH2:11][C:12]([NH:14][CH:15]2[CH2:18][N:17]([S:19]([O-:22])(=[O:21])=[O:20])[C:16]2=[O:23])=[O:13])[N:10]=1.[Na+:24]

참가 물질

4

반응물 2

HCID 5366415Metam-sodiumHCID 23695025Sodium 3-[2-(2-chloroacetamido-4-thiazolyl)acetamido]-2-oxoazetidine-1-sulfonate

생성물 1

HCID 23695028Sodium 3-[2-(2-amino-4-thiazolyl)acetamido]2-oxoazetidine-1-sulfonate수율 36.5%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

In 6 ml of water is dissolved 0.486 g of sodium 3-[2-(2-chloroacetamido-4-thiazolyl)acetamido]-2-oxoazetidine-1-sulfonate, and to the solution is added 0.154 g of sodium N-methyldithiocarbamate under ice-cooling and stirring. The mixture is treated as described in Example 3 to obtain 0.144 g of sodium 3-[2-(2-amino-4-thiazolyl)acetamido]2-oxoazetidine-1-sulfonate.

후처리

  1. temperaturecooling
  2. additionThe mixture is treated

출처 및 근거

ORD 기록
ord-a6e300199ee0492ba34203c4a53136ad
출처 데이터셋
uspto-grants-1985_10
특허 번호
US04550105

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