HCID 19027062, 화합물 → HCID 19027045, 화합물
반응식
Br[C:2]1[C:3]2[CH:18]=[CH:17][CH:16]=[N:15][C:4]=2[C:5]2[NH:6][C:7](=[O:14])[C:8](=[O:13])[N:9]([OH:12])[C:10]=2[CH:11]=1>CN(C)C=O.[Pd]>[OH:12][N:9]1[C:10]2[CH:11]=[CH:2][C:3]3[CH:18]=[CH:17][CH:16]=[N:15][C:4]=3[C:5]=2[NH:6][C:7](=[O:14])[C:8]1=[O:13]참가 물질
4
실험 절차
0.3 g (1.0 mmol) 6-Bromo-4-hydroxypyrido[2,3-f]quinoxaline-2,3(1H,4H)-dione in 20 ml dimethylformamide was hydrogenated at atm. pressure by using 300 mg Pd/c (5%) as a catalyst. The reaction mixture was filtered and the filtrate was evaporated in vacuo. The residue was stirred with ethanol and the precipitate was filtered off to give 0.2 g (90%) of 4-hydroxypyrido[2,3-f]quinoxaline-2,3(1H,4H)-dione. M.p. decomp. MS m/z: 229 (M+, 25%), 212 (100%), 185 (45%).
후처리
- filtrationThe reaction mixture was filtered
- customthe filtrate was evaporated in vacuo
- filtrationthe precipitate was filtered off
출처 및 근거
- ORD 기록
- ord-edb812a4baca4b7a91ba3e1f04010bd3
- 출처 데이터셋
- uspto-grants-1992_10
- 특허 번호
- US05153195
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