L-Alanine → N-(3-Mercaptopropanoyl)-N-methyl-L-leucine

반응식

CN[C@H](C(O)=O)CC(C)C.N[C@H](C(O)=O)C.C([S:25][CH2:26][CH2:27][C:28]([N:30]([CH3:39])[C@H:31]([C:36]([OH:38])=[O:37])[CH2:32][CH:33]([CH3:35])[CH3:34])=[O:29])(=O)C1C=CC=CC=1.N[C@H](C(O)=O)CC(C)C>>[SH:25][CH2:26][CH2:27][C:28]([N:30]([CH3:39])[C@H:31]([C:36]([OH:38])=[O:37])[CH2:32][CH:33]([CH3:35])[CH3:34])=[O:29]

참가 물질

반응물 4

HCID 5950L-Alanine

HCID 6106L-Leucine

HCID 2777993N-Methylleucine

HCID 86735141N-(3-benzoylthiopropanoyl)-N-methyl-L-leucine

생성물 1

HCID 53978361N-(3-Mercaptopropanoyl)-N-methyl-L-leucine

실험 절차

By substituting N-methyl-L-leucine for the L-alanine in the procedure of Example 1, and then treating the product by the procedure of Example 2, N-(3-benzoylthiopropanoyl)-N-methyl-L-leucine, and N-(3-mercaptopropanoyl)-N-methyl)-L-leucine are obtained.