2-Amino-5-bromo-1,3,4-thiadiazole → N-[4-[3-((3-Methylpyrrolidin-1-yl)methyl)phenoxy]butyl]1,3,4-thiadiazole-2,5-diamine

HRID 4654노트

반응식

HRID 4654 반응식
[CH3:1][CH:2]1[CH2:6][CH2:5][N:4]([CH2:7][C:8]2[CH:9]=[C:10]([CH:17]=[CH:18][CH:19]=2)[O:11][CH2:12][CH2:13][CH2:14][CH2:15][NH2:16])[CH2:3]1.Br[C:21]1[S:25][C:24]([NH2:26])=[N:23][N:22]=1>>[CH3:1][CH:2]1[CH2:6][CH2:5][N:4]([CH2:7][C:8]2[CH:9]=[C:10]([CH:17]=[CH:18][CH:19]=2)[O:11][CH2:12][CH2:13][CH2:14][CH2:15][NH:16][C:21]2[S:25][C:24]([NH2:26])=[N:23][N:22]=2)[CH2:3]1

참가 물질

3

반응물 2

HCID 36508832-Amino-5-bromo-1,3,4-thiadiazoleHCID 201514934-[3-[(3-Methylpyrrolidin-1-yl) methyl]-phenoxy]-butanamine

생성물 1

HCID 20151478N-[4-[3-((3-Methylpyrrolidin-1-yl)methyl)phenoxy]butyl]1,3,4-thiadiazole-2,5-diamine

실험 절차

The compound is prepared by a method analogous to that of Example 51 from 4-[3-[(3-methylpyrrolidin-1-yl) methyl]-phenoxy]-butanamine and 5-bromo-1,3,4-thiadiazole-2-amine.

출처 및 근거

ORD 기록
ord-bf3b640751c84f7a99cdc5a255094fe4
출처 데이터셋
uspto-grants-1988_02
특허 번호
US04727081

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