Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butanol → N-boc-4-chlorobenzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butanol | HCID 6386 | — |
| 반응물 | 4-Chlorobenzenesulfonyl isocyanate | HCID 138587 | — |
| 생성물 | N-boc-4-chlorobenzenesulfonamide | HCID 14796817 | — |
반응 단계
The commercially available p-chlorophenylsulfonyl isocyanate (15.0 g, 58.6 mmol) is added dropwise to t-butanol (90 ml) and the mixture is allowed to stir at room temperature for 60 hours. The solvent is evaporated and the white solid is recrystallized from hexane and ethylacetate to obtain N-t-butoxycarbonyl-p-chlorophenylsulfonamide, m.p. 98°-99° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05153214 |
| 출처 데이터셋 | uspto-grants-1992_10 |
| ORD ID | ord-c6fefe3fbe4c4b8ba246ce545c3a9649 |
| 출처 메모 | uspto-grants-1992_10 |