Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → 2-(p-Fluorobenzoyl)-3-methoxy-2-pentenonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | 1,1,1-Trimethoxypropane | HCID 141145 | — |
| 반응물 | p-Fluorobenzoylacetonitrile | HCID 2783172 | — |
| 생성물 | 2-(p-Fluorobenzoyl)-3-methoxy-2-pentenonitrile | HCID 53800056 | — |
반응 단계
A solution containing 30 g. of (p-fluorobenzoyl)acetonitrile, 36.4 g. of trimethylorthopropionate and 57 g. of acetic anhydride is heated in an oil bath at 130° for 3 hours. The ethanol and excess acetic anhydride is distilled off and the residue is diluted with chloroform. The chloroform solution is passed quickly through Magnesol® and concentrated, then cooled to produce the title product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04173650 |
| 출처 데이터셋 | uspto-grants-1979_11 |
| ORD ID | ord-2829d8a5983b42ecacf78f16a0bc6537 |
| 출처 메모 | uspto-grants-1979_11 |