Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 2-chloroacrylate → 5-Chloro-5-methoxycarbonyl-3-thiapentanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 2-chloroacrylate | HCID 6659 | — |
| 반응물 | 2-Mercaptoacetamide | HCID 12961 | — |
| 반응물 | 1,4-Dioxane | HCID 31275 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 5-Chloro-5-methoxycarbonyl-3-thiapentanamide | HCID 19875485 | — |
반응 단계
2-Mercaptoacetamide (18.79 g) was stirred in a mixture of dry 1,4-dioxan (200 ml) and dry pyridine (33.5 ml)) whilst methyl 2-chloroacrylate (24.88 g) was added dropwise over 15 minutes. The mixture was stirred for 1 hour then stood overnight. The resultant mixture contained the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05153330 |
| 출처 데이터셋 | uspto-grants-1992_10 |
| ORD ID | ord-7ee7a85c10d545b4b1ed1df425ca1296 |
| 출처 메모 | uspto-grants-1992_10 |