Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-bromobutanimide → Methyl 4'-bromomethylbiphenyl-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | Methyl 3-(4-methylphenyl)benzoate | HCID 1394187 | — |
| 촉매 | Azobisisobutyronitrile | HCID 6547 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | Methyl 4'-bromomethylbiphenyl-3-carboxylate | HCID 12019907 | 100.4% |
반응 단계
A solution of 7.31 g of Methyl 4'-methylbiphenyl-3-carboxylate, 5.75 g of N-bromosuccinimide, 0.125 g of azo(bisisobutyronitrile), and 500 mL of carbon tetrachloride was refluxed for 3 hours. After cooling to room temperature the resulting suspension was filtered and then concentrated in vacuo to provide 9.90 g of crude methyl 4'-bromomethylbiphenyl-3-carboxylate which was used in a subsequent reaction without further purification; NMR (200 MHz, CDCl3): δ8.28 (s, 1H); 8.05 (d, 1H); 7.79 (d, 1H); 7.67-7.48 (m, 5H); 4.55 (s, 2H); 3.98 (s, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05153197 |
| 출처 데이터셋 | uspto-grants-1992_10 |
| ORD ID | ord-fb9f0ef8dd064a8ea1b7c299cb90de20 |
| 출처 메모 | uspto-grants-1992_10 |