Butanoyloxy chloride → 4-Butanoyloxy-5-chloro-2-pyridone

반응식

[Cl:1][C:2]1[C:3]([OH:9])=[CH:4][C:5](=[O:8])[NH:6][CH:7]=1.[C:10](OCl)(=[O:14])[CH2:11][CH2:12][CH3:13]>>[C:10]([O:9][C:3]1[C:2]([Cl:1])=[CH:7][NH:6][C:5](=[O:8])[CH:4]=1)(=[O:14])[CH2:11][CH2:12][CH3:13]

참가 물질

반응물 2

HCID 18444075Butanoyloxy chloride

HCID 54679224Gimeracil

생성물 1

HCID 140496444-Butanoyloxy-5-chloro-2-pyridone수율 13%

실험 절차

The general procedure of Example 3 was followed using 2.00 g of 5-chloro-4-hydroxy-2-pyridone and 2.20 g of butanoyloxy chloride, thereby producing 0.38 g of the title compound in a yield of 13%.

출처 및 근거

ORD 기록: ord-03bc670560f2496da295f5331298e9e0
출처 데이터셋: uspto-grants-1992_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05155113

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