2-Chlorobenzoyl chloride → 6-(2-Chlorobenzoyloxy)-3-cyano-2-hydroxypyridine

HRID 466166노트

반응식

HRID 466166 반응식
[C:1]([C:3]1[C:4]([OH:10])=[N:5][C:6]([OH:9])=[CH:7][CH:8]=1)#[N:2].[Cl:11][C:12]1[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=1[C:14](Cl)=[O:15]>>[Cl:11][C:12]1[CH:20]=[CH:19][CH:18]=[CH:17][C:13]=1[C:14]([O:9][C:6]1[N:5]=[C:4]([OH:10])[C:3]([C:1]#[N:2])=[CH:8][CH:7]=1)=[O:15]

참가 물질

3

반응물 2

HCID 691102-Chlorobenzoyl chlorideHCID 178510101HCID 178510101, 화합물

생성물 1

HCID 1785100976-(2-Chlorobenzoyloxy)-3-cyano-2-hydroxypyridine수율 55%

실험 절차

The general procedure of Example 81 was followed using 2.00 g of 3-cyano-2,6-dihydroxypyridine and 2.57 g of 2-chlorobenzoyl chloride, thereby producing 2.21 g of the title compound in a yield of 55%.

출처 및 근거

ORD 기록
ord-181480fe4d68432e921cbe6ff13f3881
출처 데이터셋
uspto-grants-1992_10
특허 번호
US05155113

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