Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isobutyl chloroformate → Morphine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isobutyl chloroformate | HCID 62365 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 반응물 | HCID 131710346 | HCID 131710346 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Morphine | HCID 5288826 | — |
반응 단계
O3 -Carboxymethyl morphine (3.43 g) and 1.31 ml isobutyl chloroformate were combined in 30 ml DMF at 0°. The resulting clear solution was then added to a stirring solution of 2.88 g BSA and 13 g NaHCO3 in 600 ml of water at 0°. Addition was carried out by means of a syringe with its tip below the solution surface. The solution was stirred in a cold room overnight.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04174384 |
| 출처 데이터셋 | uspto-grants-1979_11 |
| ORD ID | ord-e97ed492edc14387bce9f58b66b21d96 |
| 출처 메모 | uspto-grants-1979_11 |