1-Amino 2-nitro-4-(2,2-dichloro-1-methylethenyl) benzene → 1,2-Diamino-4-(2,2-dichloro-1-methylethenyl) benzene

HRID 46622노트

반응식

HRID 46622 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:12])=[C:9]([Cl:11])[Cl:10])=[CH:4][C:3]=1[N+:13]([O-])=O>[Fe].C(O)C>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:12])=[C:9]([Cl:10])[Cl:11])=[CH:4][C:3]=1[NH2:13]

참가 물질

4

반응물 1

HCID 213924321-Amino 2-nitro-4-(2,2-dichloro-1-methylethenyl) benzene

생성물 1

HCID 545190211,2-Diamino-4-(2,2-dichloro-1-methylethenyl) benzene

시약·촉매·용매 2

HCID 23925Iron촉매HCID 702Ethanol용매

실험 절차

A mixture of 2.1 g. (8.5 mmoles) of 1-amino 2-nitro-4-(2,2-dichloro-1-methylethenyl) benzene 2.1 g. (0.038 moles) of iron powder is suspended in 80 ml. of 40% ethanol and refluxed for 30 minutes. The reaction mixture is filtered while hot, the solid material washed with ethanol and extracted with chloroform and evaporated to dryness in vacuo affording 1.66 g. of a brown glassy substance, which is used as is in the next step.

후처리

  1. additionA mixture of 2.1 g
  2. filtrationThe reaction mixture is filtered while hot, the solid material
  3. washwashed with ethanol
  4. extractionextracted with chloroform
  5. customevaporated to dryness in vacuo
  6. customaffording 1.66 g

출처 및 근거

ORD 기록
ord-a98c89a3bfa24d5f82668d0f52283d80
출처 데이터셋
uspto-grants-1979_11
특허 번호
US04174400

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