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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 466656생성일: 2026년 10월 25일

Triethylamine → 3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-N-tricyclo[3.3.1.13,7]dec-1-ylpropanamide

https://huagongshe.com/reaction/466656

반응식

참여 물질

역할이름HCID투입량
반응물TriethylamineHCID 8471—
반응물2,6-Di-tert-butyl-4-mercaptophenolHCID 70370—
반응물N-(Adamantan-1-yl)prop-2-enimidic acidHCID 284637—
용매MethanolHCID 887—
생성물3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-N-tricyclo[3.3.1.13,7]dec-1-ylpropanamideHCID 14986564—

반응 단계

Following the method of Example 4, 2,6-bis(1,1-dimethylethyl)-4-mercaptophenol (1.19 g, 0.005 mole), the title compound of Example 5 (1.03 g, 0.005 mole) and triethylamine (0.5 ml) were stirred in methanol (100 ml) for 12 hours at room temperature under argon. The solvent and triethylamine were removed on a rotary evaporator and the product purified by chromatography on silica, recrystallized from ethyl aceate/hexane, filtered and dried in vacuo, m.p. ca. 172.5°-173.5° C.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05157053
출처 데이터셋uspto-grants-1992_10
ORD IDord-b19c1f6cb3bb40d185dfbc392d006638
출처 메모uspto-grants-1992_10