Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloromethyl pivalate → Ticlopidine Hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloromethyl pivalate | HCID 87885 | — |
| 반응물 | N-((2-chlorophenyl)methyl)thiophene-3-ethylamine | HCID 6454012 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | Ticlopidine Hydrochloride | HCID 65335 | 51% |
반응 단계
66.5 g (0.44 M) chloromethyl pivalate is reacted by heating, for 3 hours, with a solution of 103 g (0.4 M) N-(2-chloro-benzyl)-2-(2-thienyl)ethylamine in 300 ml dimethylsulfoxide, to give the title compound in a yield of 51%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04174448 |
| 출처 데이터셋 | uspto-grants-1979_11 |
| ORD ID | ord-e1e3cd2e741d47f5826cb8f92d901749 |
| 출처 메모 | uspto-grants-1979_11 |