Ethyl isocyanoacetate → Ethyl 3-ethyl-4-methyl-1H-pyrrole-2-carboxylate

반응식

C(O[CH:5]([CH2:11][CH3:12])[CH:6]([N+]([O-])=O)[CH3:7])(=O)C.[N+:13]([CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])#[C-:14]>>[CH2:11]([C:5]1[C:6]([CH3:7])=[CH:14][NH:13][C:15]=1[C:16]([O:18][CH2:19][CH3:20])=[O:17])[CH3:12]

참가 물질

반응물 2

HCID 533707Ethyl isocyanoacetate

HCID 11805252HCID 11805252, 화합물

생성물 1

HCID 11789832Ethyl 3-ethyl-4-methyl-1H-pyrrole-2-carboxylate

실험 절차

reacting 3-acetoxy-2-nitropentane with ethyl isocyanoacetate in the presence of a nonnucleophilic base to form ethyl 3-ethyl-4-methylpyrrole-2-carboxylate;

출처 및 근거

ORD 기록: ord-114f1ab515e7497b931546b61df6388a
출처 데이터셋: uspto-grants-1992_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05159065

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