Thionyl Chloride → HCID 14699636, 화합물

반응식

[F:1][C:2]1([Cl:9])[CH2:4][C:3]1([CH3:8])[C:5](O)=[O:6].S(Cl)([Cl:12])=O>>[F:1][C:2]1([Cl:9])[CH2:4][C:3]1([CH3:8])[C:5]([Cl:12])=[O:6]

참가 물질

반응물 2

HCID 24386Thionyl Chloride2회

HCID 14699634128230-79-5

생성물 1

HCID 14699636HCID 14699636, 화합물수율 97%

실험 절차

In a distillation equipment, a mixture of 51 g (0.33 mol) of 2-fluoro-2-chloro-1-methylcyclopropanecarboxylic acid and 60 g (0.5 mol) of thionyl chloride is heated slowly with stirring, during which process excess thionyl chloride distils over first and the desired product later. In this manner, 54 g (97% of theory) of 2-fluoro-2-chloro-1-methylcyclopropanecarbonyl chloride are obtained in the form of a liquid of boiling point 82-85° C./ 100 mbar.

후처리

temperatureis heated slowly
customdistils over first and the desired product later

출처 및 근거

ORD 기록: ord-4072ad8f472447ed97e0f4eb2edbd195
출처 데이터셋: uspto-grants-1992_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05159111

반응 노트

불러오는 중…