Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl-9-trityloxy-nonanoate → Dodecanoic acid, 12-(triphenylmethoxy)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl-9-trityloxy-nonanoate | HCID 42624366 | — |
| 반응물 | Methyl 6-trityloxy-hexanoate | HCID 67198977 | — |
| 반응물 | Methyl-12-trityloxy-dodecanoate | HCID 67200799 | — |
| 생성물 | Dodecanoic acid, 12-(triphenylmethoxy)- | HCID 10790077 | — |
반응 단계
Hydrolysis of the methyl ester of 15a, 15b, and 15c was carried out under basic conditions, followed by an acidic work up, during which the pH was maintained above 4 to prevent trityl deprotection. After recrystallization for solid product or flash chromatography for oil products, 6-trityloxyhexanoic acid 16a, 9-trityloxynonanoic acid 16b and 12-trityloxydodecanoic acid 16c were isolated, providing aliphatic side-chains that were ready to be coupled to 12 and 13.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08623326B2 |
| 출처 데이터셋 | uspto-grants-2014_01 |
| ORD ID | ord-0c3f2de7ecae4ff483c3d51b7ba30cc8 |
| 출처 메모 | uspto-grants-2014_01 |