Water → Triphenylen-2-ol

HRID 467417노트

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HRID 467417 반응식
C[O:2][C:3]1[CH:20]=[CH:19][C:18]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=1.B(Br)(Br)Br.[B].O>C(Cl)Cl>[OH:2][C:3]1[CH:20]=[CH:19][C:18]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=1

참가 물질

5

반응물 3

HCID 962WaterHCID 587694502-MethoxytriphenyleneHCID 86647723Boron boron tribromide

생성물 1

HCID 3016112Triphenylen-2-ol수율 95.1%

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

반응 조건

온도
-78 °C

실험 절차

Under an argon atmosphere, 13.9 g of 2-methoxytriphenylene was placed in a flask, and 300 mL of methylene chloride was added. The reaction solution was cooled to −78° C., and 54 mL of a solution of 1M boron boron tribromide in methylene chloride was dropwise added thereto. The reaction solution was stirred for 5 hours while increasing temperature of the reaction solution to room temperature. 100 mL of water was added to the reaction solution, followed by filtration. The resulting solid was washed with water and methanol to obtain 12.5 g (yield: 95%) of 2-hydroxytriphenylene.

후처리

  1. temperaturewhile increasing temperature of the reaction solution to room temperature
  2. filtrationfollowed by filtration
  3. washThe resulting solid was washed with water and methanol

출처 및 근거

ORD 기록
ord-0e905611116c471e947e53fab1e5cbb2
출처 데이터셋
uspto-grants-2014_01
특허 번호
US08623520B2

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