Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → Dihydroandrostenedione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Epiandrosterone | HCID 441302 | — |
| 반응물 | Jones' reagent | HCID 131709961 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | Dihydroandrostenedione | HCID 222865 | 95.1% |
반응 단계
To the mixture of 6 (5 g, 17.2 mmol) and 75 ml acetone at room temperature 1.5 ml of Jones reagent (CrO3, H2SO4, H2O) was added by drops. After the reaction was completed, NaOH was added, liquid phase was separated and then 90 ml water was added. The resulting precipitate was filtered off to afford product 7 (4.72 g, 94%). M.p. 134-137° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08623849B2 |
| 출처 데이터셋 | uspto-grants-2014_01 |
| ORD ID | ord-08e7bcdbab2549c384510081d8f10672 |
| 출처 메모 | uspto-grants-2014_01 |