참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | 4-Bromophenol | HCID 7808 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | (Chloromethyl)cyclopropane | HCID 80013 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1-Bromo-4-(cyclopropylmethoxy)benzene | HCID 15625752 | — |
반응 단계
5.0 g (28.9 mmol) 4-bromophenol, 3.93 g (43.4 mmol) (chloromethyl)cyclopropane and 7.99 g (57.8 mmol) K2CO3 are added to 10 mL DMF and stirred at 80° C. over night. Afterwards the reaction mixture is diluted with water and extracted with DCM. The organic layer is dried with MgSO4, filtered and the solvent is removed in vacuo.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08623860B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_01 |
|---|
| ORD ID | ord-e2a0d5eb27f54a2c8c9fae9d97057072 |
|---|
| 출처 메모 | uspto-grants-2014_01 |
|---|
