Benzaldehyde → Cyano(phenyl)methyl 2-methylpropanoate

HRID 46753

반응식

HRID 46753 반응식
[C:1]([O:6][C:7](=[O:11])[CH:8]([CH3:10])[CH3:9])(=O)[CH:2]([CH3:4])[CH3:3].[CH:12](=O)[C:13]1[CH:18]=CC=CC=1.[C-:20]#[N:21].[Na+]>O>[C:7]([O:6][CH:1]([C:20]#[N:21])[C:2]1[CH:4]=[CH:18][CH:13]=[CH:12][CH:3]=1)(=[O:11])[CH:8]([CH3:10])[CH3:9]

참가 물질

5

반응물 3

HCID 240BenzaldehydeHCID 7346Isobutyric anhydrideHCID 8929Sodium Cyanide

생성물 1

HCID 13536647Cyano(phenyl)methyl 2-methylpropanoate

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
25 °C

실험 절차

A 100-ml round-bottomed flask equipped with a magnetic stirrer was charged with isobutyric anhydride (10 mmol), benzaldehyde (10 mmol), a mixture of alkanes (25 ml) having a boiling range of from 62° C. to 82° C., sodium cyanide (12 mmol) and water (3 ml). The mixture formed was stirred at a temperature of 25° C. The table presents the yields of the title ester after the reaction times indicated (Embodiment IV).

후처리

  1. customA 100-ml round-bottomed flask equipped with a magnetic stirrer
  2. customThe mixture formed

출처 및 근거

ORD 기록
ord-b8b0d7af08bb45c5b88e08b5a8efd0a7
출처 데이터셋
uspto-grants-1979_11
특허 번호
US04175094

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