참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 2-(3,4-Dimethoxyphenyl)-N-(2-phenylethyl)ethan-1-amine--hydrogen bromide (1/1) | HCID 3048686 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | AN-465/43411221 | HCID 215356 | 97.5% |
반응 단계
25 g of the latter hydrobromide were dissolved in 250 ml of hot water and the solution was cooled to 0° C. and made alkaline with 40 ml of 2 N sodium hydroxide. The mixture was extracted 3 times with 100 ml of ethyl acetate and the organic extracts were washed with water until the wash water had a pH of 7 to 8. The extracts were dried over sodium sulfate, were filtered and evaporated to dryness under reduced pressure to obtain 19 g of N-phenethyl-3,4-dimethoxyphenethylamine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04175136 |
|---|
| 출처 데이터셋 | uspto-grants-1979_11 |
|---|
| ORD ID | ord-667f98f9fa514bd293cae9b10b6fc01d |
|---|
| 출처 메모 | uspto-grants-1979_11 |
|---|
