Potassium Carbonate → HCID 12411034, 화합물

HRID 46775

반응식

HRID 46775 반응식
[CH2:1]([NH:9][CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([O:20][CH3:21])[CH:13]=1)[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:28](I)[CH2:29][CH3:30]>CC(C)=O>[CH2:1]([N:9]([CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([O:20][CH3:21])[CH:13]=1)[CH2:28][CH2:29][CH3:30])[CH2:2][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 336431-IodopropaneHCID 215356AN-465/43411221

생성물 1

HCID 12411034HCID 12411034, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

A solution of 8 g of N-phenethyl-3,4-dimethoxyphenethylamine, 8 g of anhydrous potassium carbonate, 11 ml of propyl iodide and 80 ml of acetone was refluxed for 6 hours and the mixture was filtered. The filtrate was evaporated to dryness and the residue was taken up in 50 ml of water. The solution was extracted with methylene chloride and the organic extracts were washed with water, dried over magnesium sulfate, filtered and evaporated to dryness to obtain 9.37 g of raw N-phenethyl-N-propyl-3,4-dimethoxyphenethylamine in the form of an oil which was used as is for the next step.

후처리

  1. filtrationthe mixture was filtered
  2. customThe filtrate was evaporated to dryness
  3. extractionThe solution was extracted with methylene chloride
  4. washthe organic extracts were washed with water
  5. dry with materialdried over magnesium sulfate
  6. filtrationfiltered
  7. customevaporated to dryness

출처 및 근거

ORD 기록
ord-35c268dcc23843a9bd9cbd95b479e615
출처 데이터셋
uspto-grants-1979_11
특허 번호
US04175136

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