Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenylmethyl 4-nitrobenzoate → Benzyl p-aminobenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenylmethyl 4-nitrobenzoate | HCID 84647 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | Benzyl p-aminobenzoate | HCID 98488 | 93.4% |
반응 단계
20.6 g of the benzyl 4-nitrobenzoate are dissolved in 350 mL dioxane and this solution is combined with 6.9 g (49.9 mmol, 0.61 eq) Raney nickel. The mixture is hydrogenated at 5 bar H2 pressure for 16 h with stirring. The catalyst is filtered off and all the volatile constituents are eliminated in vacuo. 17 g benzyl 4-aminobenzoate are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08623887B2 |
| 출처 데이터셋 | uspto-grants-2014_01 |
| ORD ID | ord-089e658d436f4ff495a9757f8aaf70de |
| 출처 메모 | uspto-grants-2014_01 |