Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Oxobutanoic Acid → ethyl acetoacetate, sodium salt
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Oxobutanoic Acid | HCID 58 | — |
| 반응물 | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | ethyl acetoacetate, sodium salt | HCID 85195 | 16,662.4% |
반응 단계
2-Oxo-butyric acid (10.0 g, 97.2 mmol) was dissolved in ethanol (100 mL) and p-toluene sulfonic acid mono hydrate (0.1 g) was added. The reaction mixture was heated to reflux for 48 h. After cooling the reaction mixture to room temperature, the ethanol was removed under reduced pressure to give 11.4 g of 2-oxo-butyric acid ethyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08623890B2 |
| 출처 데이터셋 | uspto-grants-2014_01 |
| ORD ID | ord-c64981ff2cb44d57a8bca56549480017 |
| 출처 메모 | uspto-grants-2014_01 |