Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonium Hydroxide → 2-Amino-4-chloropyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonium Hydroxide | HCID 14923 | — |
| 반응물 | 2,4-Dichloropyrimidine | HCID 77531 | — |
| 생성물 | 2-Amino-4-chloropyrimidine | HCID 223332 | — |
| 생성물 | 2-Chloro-4-aminopyrimidine | HCID 345752 | — |
반응 단계
To 2,4-Dichloropyrimidine (1.0 g, 6.7 mmol) was added 28% w/v ammonium hydroxide solution (20 mL). The mixture was stirred overnight at ambient temperature then concentrated in vacuo. The residue was dry loaded and purified by FCC eluting with 2-10% EtOH in CHCl3 to afford 2-amino-4-chloropyrimidine and 2-chloro-4-aminopyrimidine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08623859B2 |
| 출처 데이터셋 | uspto-grants-2014_01 |
| ORD ID | ord-20a8d0fd8cdf4fd5ae501cd05436ce51 |
| 출처 메모 | uspto-grants-2014_01 |