Thionyl Chloride → 3-Bromo-4-fluorobenzoyl chloride

HRID 469332

반응식

HRID 469332 반응식
[Br:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[F:11])[C:5](O)=[O:6].S(Cl)([Cl:14])=O>>[Br:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[F:11])[C:5]([Cl:14])=[O:6]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 705093-Bromo-4-fluorobenzoic acid

생성물 1

HCID 695983-Bromo-4-fluorobenzoyl chloride

실험 절차

2.17 g (9.41 mmol) 3-bromo-4-fluorobenzoic acid were mixed with 20 mL thionyl chloride and then boiled for 2 h. The reaction mixture was evaporated to dryness and coevaporated twice with toluene. The residue was reacted further as the crude product.

후처리

  1. customThe reaction mixture was evaporated to dryness
  2. customThe residue was reacted further as the crude product

출처 및 근거

ORD 기록
ord-b8ace32349b54da58a96b7c11a9daa56
출처 데이터셋
uspto-grants-2014_01
특허 번호
US08629137B2

연결된 노트

불러오는 중…