Thionyl Chloride → 3,5-Difluorobenzoyl chloride

HRID 469337

반응식

HRID 469337 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([F:11])[CH:10]=1)[C:5](O)=[O:6].S(Cl)([Cl:14])=O>>[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([F:11])[CH:10]=1)[C:5]([Cl:14])=[O:6]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 1012653,5-Difluorobenzoic acid

생성물 1

HCID 1456003,5-Difluorobenzoyl chloride

실험 절차

1.63 g (10.00 mmol) 3,5-difluoro-benzoic acid were mixed with 20 mL thionyl chloride and boiled for 2 h. The reaction mixture was evaporated to dryness and coevaporated twice with toluene. The residue was reacted further as the crude product.

후처리

  1. customThe reaction mixture was evaporated to dryness
  2. customThe residue was reacted further as the crude product

출처 및 근거

ORD 기록
ord-a565cd0d833a42f3b36e645c6b592ea7
출처 데이터셋
uspto-grants-2014_01
특허 번호
US08629137B2

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