Thionyl Chloride → 3,5-Difluorobenzoyl chloride
반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([F:11])[CH:10]=1)[C:5](O)=[O:6].S(Cl)([Cl:14])=O>>[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([F:11])[CH:10]=1)[C:5]([Cl:14])=[O:6]참가 물질
3
실험 절차
1.63 g (10.00 mmol) 3,5-difluoro-benzoic acid were mixed with 20 mL thionyl chloride and boiled for 2 h. The reaction mixture was evaporated to dryness and coevaporated twice with toluene. The residue was reacted further as the crude product.
후처리
- customThe reaction mixture was evaporated to dryness
- customThe residue was reacted further as the crude product
출처 및 근거
- ORD 기록
- ord-a565cd0d833a42f3b36e645c6b592ea7
- 출처 데이터셋
- uspto-grants-2014_01
- 특허 번호
- US08629137B2
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