Thionyl Chloride → 3-Cyano-5-fluoro-benzoic acid chloride
반응식
[C:1]([C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([F:12])[CH:11]=1)[C:6](O)=[O:7])#[N:2].S(Cl)([Cl:15])=O>>[C:1]([C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([F:12])[CH:11]=1)[C:6]([Cl:15])=[O:7])#[N:2]참가 물질
3
실험 절차
1.65 g (10.0 mmol) 3-cyano-5-fluorobenzoic acid were boiled for 2 h with 7.27 mL (100 mmol) thionyl chloride with stirring. The reaction mixture was evaporated to dryness i. vac. and coevaporated twice with toluene. The residue was reacted further as the crude product.
후처리
- customThe reaction mixture was evaporated to dryness i
- customThe residue was reacted further as the crude product
출처 및 근거
- ORD 기록
- ord-283c3667309b4b41b7d6e7a741c75ffd
- 출처 데이터셋
- uspto-grants-2014_01
- 특허 번호
- US08629137B2
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