2-(3,5-Dimethylphenyl)acetic acid → N-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]-2-(3,5-dimethylphenyl)acetamide

참여 물질

역할	이름	HCID	투입량
반응물	2-(3,5-Dimethylphenyl)acetic acid	HCID 4749495	—
반응물	2-amino-4-(4-chlorophenyl)phthalazin-1(2H)-one	HCID 67161367	—
생성물	N-[4-(4-chlorophenyl)-1-oxophthalazin-2(1H)-yl]-2-(3,5-dimethylphenyl)acetamide	HCID 53239111	—

반응 단계

The product of Example 86A and 2-(3,5-dimethylphenyl)acetic acid were treated using a method similar to that described in Example 57 to give the title compound. 1H NMR (500 MHz, DMSO-d6/Deuterium Oxide) δ ppm 8.41-8.43 (m, 1H), 7.93-8.04 (m, 2H), 7.72-7.74 (m, 1H), 7.59-7.69 (m, 4H), 6.98-6.99 (bs, 2H), 6.90-6.91 (bs, 1H), 3.60 (s, 2H), 2.26 (s, 6H); MS (ESI−) M/Z 416 (M−H)−.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08629143B2
출처 데이터셋	uspto-grants-2014_01
ORD ID	ord-299861c7b00c499e8853254b35253e10
출처 메모	uspto-grants-2014_01