Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Aminopyridazine → 5-cyclohexyl-N-pyridazin-4-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Aminopyridazine | HCID 298492 | — |
| 반응물 | 5-Cyclohexyl-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 71293952 | — |
| 생성물 | 5-cyclohexyl-N-pyridazin-4-yl-6-(2,2,2-trifluoro-ethoxy)-nicotinamide | HCID 71294298 | — |
반응 단계
This compound was prepared following the same procedure as described in Example 11 using 5-cyclohexyl-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (Example 4b) (100 mg, 0.33 mmol) and 4-pyridazinamine (CAN 20744-39-2, 31.4 mg, 0.33 mmol) as starting materials; off white solid (60 mg, 47.8%). MS (ESI): 381.4 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08629166B2 |
| 출처 데이터셋 | uspto-grants-2014_01 |
| ORD ID | ord-63f01adf23b44b20887b196c114af723 |
| 출처 메모 | uspto-grants-2014_01 |