Ethyl o-cyanomethylcinnamate → Ethyl o-(cyanomethyl)hydrocinnamate

HRID 46989노트

반응식

HRID 46989 반응식
[C:1]([CH2:3][C:4]1[CH:16]=[CH:15][CH:14]=[CH:13][C:5]=1[CH:6]=[CH:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])#[N:2].[H][H]>C(O)C.[Pd]>[C:1]([CH2:3][C:4]1[CH:16]=[CH:15][CH:14]=[CH:13][C:5]=1[CH2:6][CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])#[N:2]

참가 물질

5

반응물 2

HCID 53697120Ethyl o-cyanomethylcinnamateHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 54486935Ethyl o-(cyanomethyl)hydrocinnamate

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

Ethyl o-(cyanomethyl)cinnamate (75.1 g., 0.35 mole) is dissolved in ethanol (300 ml.) and hydrogenated at a pressure of 1 atmosphere and room temperature over 2.5 g. of a 5% palladium on charcoal catalyst. When the theoretical amount of hydrogen (0.35 mole) has been absorbed, the catalyst is filtered off and the ethanol removed by distillation at reduced pressure to yield ethyl o-(cyanomethyl)hydrocinnamate.

후처리

  1. customhydrogenated at a pressure of 1 atmosphere and room temperature over 2.5 g
  2. filtrationthe catalyst is filtered off
  3. customthe ethanol removed by distillation at reduced pressure

출처 및 근거

ORD 기록
ord-5a2238bf2cb243deb54f41fa66ed13b8
출처 데이터셋
uspto-grants-1979_11
특허 번호
US04175203

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