참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Ethyl 2-(2-(4-cyanophenyl)pyridin-3-ylthio)-2-methylpropanoate | HCID 67997044 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-(2-(4-Cyanophenyl)pyridin-3-ylthio)-2-methylpropanoic acid | HCID 67997363 | 96.6% |
반응 단계
A mixture of ethyl 2-(2-(4-cyanophenyl)pyridin-3-ylthio)-2-methylpropanoate (0.137 g, 0.42 mmol), aqueous sodium hydroxide solution (1M, 1 mL) and methanol (2 mL) was stirred at 60° C. for 12 hours. The reaction mixture was concentrated to remove methanol, acidified and filtered to obtain 2-(2-(4-cyanophenyl)pyridin-3-ylthio)-2-methylpropanoic acid as a white powder (0.121 g, 96%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08629278B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_01 |
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| ORD ID | ord-2c608e5c93774fffbf61e71820397010 |
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| 출처 메모 | uspto-grants-2014_01 |
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