Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl cyanoacetate → HCID 178509384, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl cyanoacetate | HCID 7764 | — |
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 3-Pyridinecarboxaldehyde, 2-amino- | HCID 737633 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | HCID 178509384 | HCID 178509384 | — |
반응 단계
A mixture of 2-aminonicotinaldehyde (2.44 g., 0.02 m), ethyl α-cyanoacetate (4.52 g., 0.04 m.), absolute ethanol (50 ml.) and piperidine (0.5 ml) is stirred under reflux. After 1 hour, the solution is cooled to 0°-4° C. The yellow solid is filtered and dried to yield 2.5 g. (73%) of 2-hydroxy-3-cyano-1,8-naphthyridines, m.p. 300° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04176183 |
| 출처 데이터셋 | uspto-grants-1979_11 |
| ORD ID | ord-2e9252f1b37d4a8f95e6b4a6feb9158b |
| 출처 메모 | uspto-grants-1979_11 |