Acetic Acid → 5,6-Dimethoxy-3[4(tetrahydropyran-2-carbonyl) piperazinyl]methylene oxindole
반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[NH:8][C:7](=[O:14])[C:6]2=[CH:15]O.[O:17]1[CH2:22][CH2:21][CH2:20][CH2:19][CH:18]1[C:23]([N:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1)=[O:24].C(O)(=O)C>C1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:9](=[CH:10][C:11]=1[O:12][CH3:13])[NH:8][C:7](=[O:14])[C:6]2=[CH:15][N:28]1[CH2:29][CH2:30][N:25]([C:23]([CH:18]2[CH2:19][CH2:20][CH2:21][CH2:22][O:17]2)=[O:24])[CH2:26][CH2:27]1참가 물질
5
실험 절차
5.00 g. of 5,6-dimethoxy-3-hydroxymethylene oxindole, 5,6 g. 1-(tetrahydropyran-2-carbonyl)piperazine and 2.1 g. acetic acid in 60 ml. benzene was reacted as described in Example 5 to give 6.18 g. of product, m.p. 208°-210° C.