Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodine → 5'-Iodo-m-terphenyl
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodine | HCID 807 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | M-Terphenyl | HCID 7076 | — |
| 반응물 | Hydroiodic acid dihydrate | HCID 85613701 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5'-Iodo-m-terphenyl | HCID 13067230 | 58.9% |
반응 단계
A three neck flask was charged with 250 g of m-terphenyl (manufactured by Aldrich Co., Ltd.), 50 g of hydroiodic acid dihydrate, 75 g of iodine, 750 mL of acetic acid and 25 mL of cone, sulfuric acid, and they were reacted at 70° C. for 3 hours. After reaction, the solution was poured into 5 L of methanol and then stirred for one hour. This was separated by filtration, and crystal obtained was refined by means of column chromatography and recrystallized from acetonitrile to obtain 64 g of 5-phenyl-3-iodobiphenyl (intermediate 3) shown, below and 17 g of 3′-phenyl-4-iodobiphenyl (intermediate 4) shown below.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08629613B2 |
| 출처 데이터셋 | uspto-grants-2014_01 |
| ORD ID | ord-1799225de70548219040d4c1b7dc07cf |
| 출처 메모 | uspto-grants-2014_01 |