Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloroform → 4,4-Dimethyl-7-(2,4-dimethoxybenzoyl amino)-8-nitro-2H,4H-isoquinoline-1,3-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloroform | HCID 6212 | — |
| 반응물 | 2,4-Dimethoxybenzoyl chloride | HCID 2734719 | — |
| 반응물 | 1,3(2H,4H)-Isoquinolinedione, 7-amino-4,4-dimethyl-8-nitro- | HCID 11118443 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | 4,4-Dimethyl-7-(2,4-dimethoxybenzoyl amino)-8-nitro-2H,4H-isoquinoline-1,3-dione | HCID 20384991 | — |
반응 단계
2.7 gm of 4,4-dimethyl-7-amino-8-nitro-2H,4H-isoquinoline-1,3-dione were admixed with 50 ml of chloroform and 2.5 ml of triethylamine. Subsequently, 2.2 gm of 2,4-dimethoxybenzoylchloride were added, and the mixture was refluxed for 2 hours. After cooling the solution was evaporated and the precipitate was suction-filtered off and digested with water while heating.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04176184 |
| 출처 데이터셋 | uspto-grants-1979_11 |
| ORD ID | ord-4daf93f3d00e408d87d772158b269ff5 |
| 출처 메모 | uspto-grants-1979_11 |