Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Bicarbonate → 4,4-Dimethyl-7-propionylamino-8-nitro-2H,4H-isoquinoline-1,3-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 반응물 | 4,4-dimethyl-7-acetamino-8-nitro-2H,4H-isoquinoline-1,3-dione | HCID 11833171 | — |
| 용매 | Propionic anhydride | HCID 31263 | — |
| 생성물 | 4,4-Dimethyl-7-propionylamino-8-nitro-2H,4H-isoquinoline-1,3-dione | HCID 20384930 | — |
반응 단계
29.1 gm of 4,4-dimethyl-7-acetamino-8-nitro-2H,4H-isoquinoline-1,3-dione were refluxed for 4 hours with 50 ml of propionic acid anhydride. The mixture was then poured into ice water and neutralized with sodium bicarbonate. The obtained precipitate was purified on a silicagel column (eluant: chloroform/acetone 19:1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04176184 |
| 출처 데이터셋 | uspto-grants-1979_11 |
| ORD ID | ord-4924df22b6b444dcb4a340a120e8213e |
| 출처 메모 | uspto-grants-1979_11 |