Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) → 7,7-Dimethyl-2-benzyl-5-(2-morpholino-ethyl)-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione dihydrochloride

HRID 47115

반응식

HRID 47115 반응식
[CH3:1][C:2]1([CH3:24])[C:11](=[O:12])[CH:10]2[C:5](=[C:6]3[N:16]=[C:15]([CH2:17][C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)[N:14]=[C:7]3[C:8](=[O:13])[CH2:9]2)[CH:4]=[N:3]1.[ClH:25].[O:26]1[CH2:31][CH2:30][N:29]([CH2:32][CH2:33][Cl:34])[CH2:28][CH2:27]1>>[ClH:34].[ClH:25].[CH3:1][C:2]1([CH3:24])[C:11](=[O:12])[CH:10]2[C:5](=[C:6]3[N:16]=[C:15]([CH2:17][C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)[N:14]=[C:7]3[C:8](=[O:13])[CH:9]2[CH2:33][CH2:32][N:29]2[CH2:30][CH2:31][O:26][CH2:27][CH2:28]2)[CH:4]=[N:3]1

참가 물질

3

반응물 2

HCID 77210Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1)HCID 706099627,7-dimethyl-2-benzyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione

생성물 1

HCID 706103987,7-Dimethyl-2-benzyl-5-(2-morpholino-ethyl)-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione dihydrochloride

실험 절차

Prepared analogous to Example 23 from 1.6 gm of 7,7-dimethyl-2-benzyl-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione and 1.2 gm of 2-morpholino-ethyl chloride hydrochloride.

출처 및 근거

ORD 기록
ord-d0f3470974684dfab26c1ed77269735f
출처 데이터셋
uspto-grants-1979_11
특허 번호
US04176184

연결된 노트

불러오는 중…