Benzoyl isocyanate → N-(2-cyano-5-hydroxyphenylcarbamoyl)benzamide
반응식
[NH2:1][C:2]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[C:11]([N:19]=[C:20]=[O:21])(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>CC(C)=O>[C:4]([C:3]1[CH:6]=[CH:7][C:8]([OH:10])=[CH:9][C:2]=1[NH:1][C:20]([NH:19][C:11](=[O:18])[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:21])#[N:5]참가 물질
4
실험 절차
Prepared as in Example 53a, but refluxed in acetone instead of 1,4-dioxane, from 2-amino-4-hydroxybenzonitrile and benzoyl isocyanate as a yellow solid (399 mg, 94%). MS 281 (MH1).
후처리
- customPrepared as in Example 53a
출처 및 근거
- ORD 기록
- ord-c99889fac02f44b292eb4d4aaeaaa113
- 출처 데이터셋
- uspto-grants-2014_01
- 특허 번호
- US08633186B2
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