Ethyl Bromide → 2-Nitro-6-ethoxybenzonitrile

HRID 471587노트

반응식

HRID 471587 반응식
[OH:1][C:2]1[CH:9]=[CH:8][CH:7]=[C:6]([N+:10]([O-:12])=[O:11])[C:3]=1[C:4]#[N:5].[CH2:13](Br)[CH3:14]>>[N+:10]([C:6]1[CH:7]=[CH:8][CH:9]=[C:2]([O:1][CH2:13][CH3:14])[C:3]=1[C:4]#[N:5])([O-:12])=[O:11]

참가 물질

3

반응물 2

HCID 6332Ethyl BromideHCID 125032052-Hydroxy-6-nitrobenzonitrile

생성물 1

HCID 247777792-Nitro-6-ethoxybenzonitrile수율 50%

실험 절차

Prepared in a similar manner as Example 115c from 2-hydroxy-6-nitrobenzonitrile (Example 115d) and ethyl bromide to provide 2-nitro-6-ethoxybenzonitrile (192 mg, 50%).

출처 및 근거

ORD 기록
ord-b98a7f8a24654c8c870aceeb5c7fffdc
출처 데이터셋
uspto-grants-2014_01
특허 번호
US08633186B2

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