Dinitrobenzonitrile → 2-(5-(Tert-butyldimethylsilyloxy)pentyloxy)-6-nitrobenzonitrile

반응식

[C:1]([Si:5]([CH3:14])([CH3:13])[O:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12])([CH3:4])([CH3:3])[CH3:2].[N+:15]([C:18]1[CH:25]=[CH:24][CH:23]=[C:22]([N+]([O-])=O)[C:19]=1[C:20]#[N:21])([O-:17])=[O:16]>>[Si:5]([O:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][O:12][C:22]1[CH:23]=[CH:24][CH:25]=[C:18]([N+:15]([O-:17])=[O:16])[C:19]=1[C:20]#[N:21])([C:1]([CH3:4])([CH3:3])[CH3:2])([CH3:14])[CH3:13]

참가 물질

반응물 2

HCID 520718Dinitrobenzonitrile

HCID 36143185-((Tert-butyldimethylsilyl)oxy)pentan-1-ol

생성물 1

HCID 667458952-(5-(Tert-butyldimethylsilyloxy)pentyloxy)-6-nitrobenzonitrile수율 46%

실험 절차

Prepared as in Example 215c from 5-(tert-butyldimethyl-silyloxy)pentan-1-ol and 2,6-dinitrobenzonitrile as a pale yellow solid in 46% yield. MS 365 (MH+).

출처 및 근거

ORD 기록: ord-f43c4b804df44d46b4141a16e4f469ea
출처 데이터셋: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08633186B2

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