Nitric Acid → HCID 178512576, 화합물

HRID 47204

반응식

HRID 47204 반응식
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[C:4]([N+]([O-])=O)[CH:3]=1.[N+:12]([O-:15])([OH:14])=[O:13].[N:16]#[C:17][NH2:18]>CCO>[N+:12]([O-:15])([OH:14])=[O:13].[OH:8][C:5]1[CH:6]=[CH:7][C:2]([NH:1][C:17]([NH2:18])=[NH:16])=[C:3]([N+:12]([O-:15])=[O:13])[CH:4]=1

참가 물질

5

반응물 3

HCID 944Nitric AcidHCID 9864CyanamideHCID 34174194-Amino-2-Nitrophenol

생성물 1

HCID 178512576HCID 178512576, 화합물수율 54%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of 4-amino-2-nitrophenol (25 mmol, 3.85 g) in EtOH (6 mL) on an ice bath was treated with nitric acid (69% aq soln.; 1.8 mL). To this of cyanamide (50% aq. soln.; 4 mL) was added. The reaction mixture was refluxed under N2 for 22 h. The solvent was evaporated. The dark brown solid residue was washed with EtOH and was dried under high vacuum to afford the title compound as a grey solid (3.53 g, 54%).

후처리

  1. temperatureThe reaction mixture was refluxed under N2 for 22 h
  2. customThe solvent was evaporated
  3. washThe dark brown solid residue was washed with EtOH
  4. customwas dried under high vacuum

출처 및 근거

ORD 기록
ord-1668630a45044138b5579a1df16f23ff
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06699854B2

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