Pyridine → Benzoyloxymethylpyridinium chloride

HRID 4721

반응식

HRID 4721 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:7]([O:15][CH2:16][Cl:17])(=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[K+].[Br-]>>[Cl-:17].[C:7]([O:15][CH2:16][N+:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)(=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

참가 물질

4

반응물 3

HCID 1049PyridineHCID 79257Chloromethyl benzoateHCID 253877Potassium Bromide

생성물 1

HCID 12602695Benzoyloxymethylpyridinium chloride

실험 절차

A mixture containing 0.79 g (0.01 mol) pyridine and 1.7 g (0.01 mol) chloromethyl benzoate was allowed to react at ambient temperature for 24 hr. Trituration in anhydrous ether followed by filtration under nitrogen gave 1.2 g (0.005 mol), 50%, 29, mp 197°-199° (dec); ir (KBr) 3440, 3020, 1710, 1610, 1475, 1265, 1150, 1085, 870 and 700 cm-1 ; pmr (D2O) δ 7.0-10.0 (m, 10H) and 6.6 (s, 2H) ppm.

후처리

  1. customto react at ambient temperature for 24 hr
  2. filtrationTrituration in anhydrous ether followed by filtration under nitrogen
  3. customgave 1.2 g (0.005 mol), 50%, 29, mp 197°-199° (dec)

출처 및 근거

ORD 기록
ord-d6803dbfbc1e4f0fbfab242ee261a3d9
출처 데이터셋
uspto-grants-1988_02
특허 번호
US04727151

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